Incidencia de dislipidemia por obesidad en pacientes del Centro de Salud Iscozacín, Oxapampa, Pasco, Perú en el periodo enero -diciembre del 2021

Abstract

Las dislipidemias, asociadas a sobrepeso y obesidad, como factores predisponentes de enfermedades cardiovasculares tienen una gran incidencia clínica, dada la alta morbimortalidad que conlleva; de ahí que el presente estudio estuvo orientado a determinar la incidencia de dislipidemia por obesidad en pacientes del Centro de Salud Iscozacín, Oxapampa, Pasco, Perú.2021, dado que hay muy poca información de estudios relacionados en estas entidades y su relación con el sobrepeso y la obesidad, para de esa manera potenciar la atención desde enfoques preventivos a los factores de riesgo que desencadenan estos trastornos, para ello se realizó una investigación correlacional y retrospectiva del total de pacientes que acudieron a dicho Centro de Salud; analizándose la incidencia de obesidad por hipercolesterolemia e hipertrigliceridemia y las variables edad, sexo, índice de masa corporal y resultados de laboratorio, tales como colesterol total y triglicéridos. Los resultados obtenidos:36 mujeres 66.7% (n=10) presentaron nivel rango crítico de colesterol,81% (n=17) presentaron nivel de riesgo y 64.3% (n=9) presentan nivel de alto riesgo.56 mujeres tuvieron un nivel de triglicéridos limítrofe siendo 65.2% (n=15) y 73.2%(n=41) presentaron nivel alto. En el estudio realizado se concluye que la incidencia de dislipidemia tanto por hipercolesterolemia e hipertrigliceridemia estuvo predominada por mujeres adultas, entre 40- 50 años.

Biology contributes to criminalistics in determining whether a bloodstain in a scene is human or animal. For this type of analysis, immunochromatographic kits produced by the forensic industry are used, but due to their high cost and limited supply, they cannot be easily purchased. , therefore samples of legal cases are not processed due to lack of this reagent; but there are homologous kits designed for the clinical field that are used to detect human hemoglobin in stool samples, they are cheap and easy to obtain, these, like forensic kits, carry specific monoclonal studies to detect human hemoglobin that could well be used in the legal area; The objective of the present work was to know the efficiency of the clinical kit of the commercial brand FOB-HI Rapid Test of CTK in the detection of human hemoglobin in blood stains of forensic cases, and the forensic use kit of the Bluestar OBTI brand was obtained as Standard Gold; With both kits, 83 bloodstains from forensic cases up to four years old were analyzed, samples that remained in the Biology Laboratory of the Toxicology Unit of the Institute of Legal Medicine of Peru; Non-human blood samples and plant extracts were also analyzed in order to determine the specificity of the FOB-HI Rapid Test kit. With the results obtained, the diagnostic accuracy and other parameters of the clinical kit were evaluated, obtaining a sensitivity of 98.79%. , specificity of 100%, efficiency 99.04%, positive predictive value of 100%, negative predictive value of 95.23%, the concordance of the clinical kit and the forensic kit was almost perfect with a kappa index of 0.97, it is concluded that both kits are compatible, and it is recommended that in the event of a shortage of the forensic kit, a clinical kit can be used, after internal quality control by the forensic laboratory.