Efectividad analgésica post exodoncia simple de la terapia profiláctiva y la terapia continuada con naproxeno sódico
Asmat Abanto, Angel Steven
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Objective: To compare the effectiveness of prophylactic therapy and continued therapy with naproxen sodium post simple extraction. Material and methods: This prospective randomized, parallel, single-blind clinical assay, was developed in the Clínica Estomatológica of Universidad Alas Peruanas Filial Trujillo. Patients who required a simple extraction by dental caries, were randomized into three groups: 30 received naproxen sodium 550 mg preoperatively and then every 12 hours, 30 received naproxen sodium 550 mg postoperatively and then every 12 hours, and 30, ibuprofen (control group) 400 mg postoperatively and then every 8 hours, according to the established criteria. The procedure was standardized and the analgesic efficacy assessed by visual analog scale, and the presence of adverse drug reactions. For the analysis of results, the Mann-Whitney U test was used, considering a significance level of 5%. Result: there is a difference between naproxen sodium therapies at 1 (p = 0,001), 8 (p = 0,000) and 24 (p = 0,001) hours post simple extraction, presenting less pain the patients treated with continued therapy. Conclusion: continued therapy with naproxen sodium showed greater effectiveness than prophylactic therapy post simple extraction.