Comparación de la exactitud diagnóstica del índice de malignidad de Jacobs y las reglas simples del análisis Internacional de Tumores de Ovario (IOTA) para cáncer de ovario
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Date
2024-01-17
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Universidad Nacional de Trujillo
Abstract
El cáncer de ovario es la tercera neoplasia ginecológica más común y cuenta con una tasa de mortalidad alta esto se atribuyó al diagnóstico tardío en etapas posteriores de la enfermedad. El desarrollo de herramientas para el diagnóstico temprano y tratamiento del cáncer de ovario tiene un impacto significativo en el pronóstico de cada paciente. Las masas anexiales siguen siendo los problemas más desafiantes en la ginecología, aunque una pequeña fracción de estas masas es maligna, un correcto diagnóstico preoperatorio es indispensable en el manejo de la patología anexial. El tratamiento y manejo de las masas anexiales depende de la diferenciación preoperatoria que es fundamental para optimizar la atención y por lo tanto la morbilidad, la mortalidad y la supervivencia del paciente. Actualmente existen varios métodos para pronosticar entre masa ovárica maligna o benigna, dentro de las cuales se cuentan a las reglas simples de simple de IOTA y el índice de Jacobs. Por lo tanto, la ejecución del siguiente trabajo de investigación permitirá comparar el índice de malignidad de Jacobs y las reglas simples de IOTA para el diagnóstico de cáncer de ovario, con el fin de disminuir morbimortalidad y establecer pautas que sirvan como evidencia científica que permita a los profesionales de salud tener herramientas para mejorar el diagnóstico y manejo de masas anexiales. Se realizará un trabajo prospectivo, descriptivo, observacional, de pruebas diagnósticas en donde se evaluarán tres variables y cuyo objetivo es calcular la sensibilidad, especificidad, valor predictivo positivo y valor predictivo negativo de cada score para diagnóstico de cáncer de ovario. Se realizará el cálculo del intervalo de confianza al 95% del estadígrafo correspondiente.
Ovarian cancer is the third most common gynecological malignancy and it has a high mortality rate, which was attributed to late diagnosis in later stages of the disease. The development of tools for the early diagnosis and treatment of ovarian cancer has a significant impact on the prognosis of each patient. Adnexal masses continue to be the most challenging problems in gynecology, although a small fraction of these masses is malignant, a correct preoperative diagnosis is essential in the management of adnexal pathology. The treatment and management of adnexal masses depends on preoperative differentiation, which is essential to optimize care and therefore patient morbidity, mortality, and survival. Currently there are several methods to predict between malignant and benign ovarian mass, among which are the simple rules of IOTA and the Jacobs Index. Therefore, the execution of the following research work will allow the comparison of the Jacobs malignancy index and the simple IOTA rules for the diagnosis of ovarian cancer, in order to reduce morbidity and mortality and establish guidelines that serve as scientific evidence that allows Health professionals have tools to improve the diagnosis and management of adnexal masses. A prospective, descriptive, observational work of diagnostic tests will be carried out where three variables will be evaluated and whose objective is to calculate the sensitivity, specificity, positive predictive value and negative predictive value of each score for diagnostic ovarian cancer. The calculation of the 95% confidence interval of the corresponding statistician will be carried out.
Ovarian cancer is the third most common gynecological malignancy and it has a high mortality rate, which was attributed to late diagnosis in later stages of the disease. The development of tools for the early diagnosis and treatment of ovarian cancer has a significant impact on the prognosis of each patient. Adnexal masses continue to be the most challenging problems in gynecology, although a small fraction of these masses is malignant, a correct preoperative diagnosis is essential in the management of adnexal pathology. The treatment and management of adnexal masses depends on preoperative differentiation, which is essential to optimize care and therefore patient morbidity, mortality, and survival. Currently there are several methods to predict between malignant and benign ovarian mass, among which are the simple rules of IOTA and the Jacobs Index. Therefore, the execution of the following research work will allow the comparison of the Jacobs malignancy index and the simple IOTA rules for the diagnosis of ovarian cancer, in order to reduce morbidity and mortality and establish guidelines that serve as scientific evidence that allows Health professionals have tools to improve the diagnosis and management of adnexal masses. A prospective, descriptive, observational work of diagnostic tests will be carried out where three variables will be evaluated and whose objective is to calculate the sensitivity, specificity, positive predictive value and negative predictive value of each score for diagnostic ovarian cancer. The calculation of the 95% confidence interval of the corresponding statistician will be carried out.
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Keywords
Reglas simples de IOTA, Indice de Malignidad Jacobs, Cáncer de Ovario