Menarquia temprana como factor de riesgo para asma bronquial. Hospital Belén de Trujillo-Perú
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Date
2022-07-22
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Universidad Nacional de Trujillo
Abstract
El asma es una enfermedad inflamatoria crónica de las vías respiratorias, en cuya patogenia intervienen diversas células y mediadores de la inflamación, condicionada en parte por factores genéticos La menarquía temprana es un sangrado vaginal transitorio y aislado o un sangrado cíclico en ausencia de otros signos de desarrollo sexual, se da en aquellas niñas menores de 10 años. Existe un papel perjudicial de la hormona sexual en las mujeres con asma antes de la menstruación, como sucede en las niñas con menarquia temprana. Este trabajo, se trata de asociar la edad de la menarquia con la salud respiratoria posterior, específicamente con el asma, sus síntomas y la reactividad bronquial. Este estudio será de tipo analítico, prospectivo, observacional, casos y controles; se realizará en el servicio de Pediatría del Hospital Belén de Trujillo, con aquellas mujeres menores de 14 años, con registro de menarquia temprana y de asma bronquial. Para el análisis estadísticos de los datos se usará test de Fisher y para evaluar factor de riesgo, se obtendrá el Odds Ratio (OR). El intervalo de confianzó será 95% y la significancia estadística de p<0,05 .
Asthma is a chronic inflammatory disease of the respiratory tract, in whose pathogenesis various cells and inflammatory mediators are involved, conditioned in part by genetic factors. Early menarche is transient and isolated vaginal bleeding or cyclical bleeding in the absence of other signs of sexual development occurs in girls under 10 years of age. There is a detrimental role of the sex hormone in women with asthma before menstruation, as in girls with early menarche. This work tries to associate the age of menarche with subsequent respiratory health, specifically with asthma, its symptoms and bronchial reactivity. This study will be analytical, prospective, observational, cases and controls; It will be carried out in the Pediatric service of the Hospital Belén of Trujillo, with those women under 14 years of age, with a record of early menarche and bronchial asthma. For the statistical analysis of the data, the Fisher test will be used and to evaluate the risk factor, the Odds Ratio (OR) will be obtained. The confidence interval will be 95% and the statistical significance of p<0.05
Asthma is a chronic inflammatory disease of the respiratory tract, in whose pathogenesis various cells and inflammatory mediators are involved, conditioned in part by genetic factors. Early menarche is transient and isolated vaginal bleeding or cyclical bleeding in the absence of other signs of sexual development occurs in girls under 10 years of age. There is a detrimental role of the sex hormone in women with asthma before menstruation, as in girls with early menarche. This work tries to associate the age of menarche with subsequent respiratory health, specifically with asthma, its symptoms and bronchial reactivity. This study will be analytical, prospective, observational, cases and controls; It will be carried out in the Pediatric service of the Hospital Belén of Trujillo, with those women under 14 years of age, with a record of early menarche and bronchial asthma. For the statistical analysis of the data, the Fisher test will be used and to evaluate the risk factor, the Odds Ratio (OR) will be obtained. The confidence interval will be 95% and the statistical significance of p<0.05
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Keywords
Asma, Menarquia, Niñas