Prevalencia de los genotipos de alto riesgo no vacunables del Virus de Papiloma Humano en pacientes del Centro de Salud Villa Victoria Porvenir en Surquillo - Lima, agosto 2021 a octubre 2022
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Date
2024
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Universidad Nacional de Trujillo
Abstract
La presente investigación tuvo como objetivo determinar la Prevalencia de los genotipos de alto riesgo no vacunables del Virus de Papiloma Humano (VPH) en pacientes del Centro de Salud Villa Victoria -Porvenir, Surquillo, Lima, se abordó una investigación retrospectivo y de carácter transversal, con un nivel descriptivo. Se incluyó a las mujeres del Programa de Prevención del Cáncer en el periodo de agosto 2021 a octubre 2022. La población se conformó de 246 historias clínicas de mujeres de 30 a 49 años, que completaron los criterios de inclusión y exclusión, con prueba molecular para el Virus de Papiloma Humano de alto riesgo. La muestra se constituyó por 223 casos con prueba molecular positiva o negativa para el Virus de Papiloma Humano. Se usó la estadística descriptiva en la determinación de la prevalencia de los genotipos de alto riesgo del Virus de Papiloma Humano con apoyo de SPSS V.24. Se determinó alto porcentaje del Virus de Papiloma Humano de alto riesgo con un IC 95% [5.9 – 13.8] correspondiente a genotipos no incluidas en las vacunas en la muestra estudiada. Así mismo, la prevalencia fue inversamente proporcional con la edad, con aumento de otros genotipos de alto riesgo, una reducción referente al genotipo 16 e indetectable genotipo 18 y una acentuada coexistencia de VPH16 con otros genotipos de alto riesgo oncogénico.
The objective of this research is to determine the prevalence of non-vaccinable high-risk genotypes of Human Papillomavirus (HPV) in patients of the Villa Victoria-Porvenir Health Center, Surquillo, Lima, a retrospective and cross-sectional research with a descriptive level. The study included women under the Cancer Prevention Program from August 2021 to October 2022. The population consisted of 246 medical records of women aged 30 to 49 years, who completed the inclusion and exclusion criteria, with molecular testing for high-risk Human Papillomavirus. The sample consisted of 223 cases with positive or negative molecular test for Human Papillomavirus. Descriptive statistics were used to determine the prevalence of high-risk genotypes of the Human Papillomavirus with the support of SPSS V.24. A high percentage of high-risk HPV was determined with a 95% CI [5.9 - 13.8] corresponding to genotypes not included in the vaccines in the sample studied. Likewise, the prevalence was inversely proportional to age, with an increase of other high risk genotypes, a reduction regarding genotype 16 and undetectable genotype 18 and an accentuated coexistence of HPV16 with other genotypes of high oncogenic risk.
The objective of this research is to determine the prevalence of non-vaccinable high-risk genotypes of Human Papillomavirus (HPV) in patients of the Villa Victoria-Porvenir Health Center, Surquillo, Lima, a retrospective and cross-sectional research with a descriptive level. The study included women under the Cancer Prevention Program from August 2021 to October 2022. The population consisted of 246 medical records of women aged 30 to 49 years, who completed the inclusion and exclusion criteria, with molecular testing for high-risk Human Papillomavirus. The sample consisted of 223 cases with positive or negative molecular test for Human Papillomavirus. Descriptive statistics were used to determine the prevalence of high-risk genotypes of the Human Papillomavirus with the support of SPSS V.24. A high percentage of high-risk HPV was determined with a 95% CI [5.9 - 13.8] corresponding to genotypes not included in the vaccines in the sample studied. Likewise, the prevalence was inversely proportional to age, with an increase of other high risk genotypes, a reduction regarding genotype 16 and undetectable genotype 18 and an accentuated coexistence of HPV16 with other genotypes of high oncogenic risk.
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Keywords
Papiloma Virus Humano, Reacción en Cadena de la Polimerasa, Genotipos de alto riesgo no vacunables