Tiempo de llenado capilar prolongado como factor pronóstico de mortalidad en pacientes con shock séptico
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Date
2024-08-12
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Universidad Nacional de Trujillo
Abstract
El shock séptico sigue siendo un factor de riesgo alto para muerte en individuos enfermos. El estado de sepsis, es la disfunción debida a la respuesta no apropiada del huésped a infección y llega afectar cerca a 1 de cada 3 individuos críticos. A nivel mundial, provoca 6 millones de muertes.
La perfusión periférica aparece como un objetivo alternativo prometedor. En este sentido el excelente pronóstico asociado con normalización del tiempo de llenado capilar, el tiempo de respuesta rápida a la carga de fluidos, además de su simplicidad y disponibilidad en entornos de recursos limitados, constituyen un sólido antecedente para promover estudios que evalúen su utilidad para guiar la reanimación con líquidos.
Entre diversos índices complementarios, lapso de llenado capilar es un parámetro de valoración de choque que tiende a extenderse en individuos con sepsis; no obstante, este parámetro se establece de forma subjetiva, y su valoración escasea de objetividad y reproducibilidad. Sin embargo, si llega a cuantificar y es evaluado con un grado acrecentado de precisión, el tiempo de llenado capilar proporciona una evaluación complementaria de la circulación, aprovechando al máximo las características de este marcador.
Abstract Septic shock remains a high risk factor for death in sick individuals. The state of sepsis is the dysfunction due to the inappropriate response of the host to infection and affects about 1 in 3 critically ill individuals. Worldwide, it causes 6 million deaths. Peripheral perfusion appears as a promising alternative target. In this sense, the excellent prognosis associated with normalization of capillary refill time, the rapid response time to fluid loading, in addition to its simplicity and availability in limited resource settings, constitute a solid background to promote studies that evaluate its usefulness for guide fluid resuscitation. Among various complementary indices, capillary refill time is a shock assessment parameter that tends to be extended in individuals with sepsis; However, this parameter is established subjectively, and its assessment lacks objectivity and reproducibility. However, if it is quantified and evaluated with an increased degree of precision, capillary refill time provides a complementary assessment of circulation, taking full advantage of the characteristics of this marker.
Abstract Septic shock remains a high risk factor for death in sick individuals. The state of sepsis is the dysfunction due to the inappropriate response of the host to infection and affects about 1 in 3 critically ill individuals. Worldwide, it causes 6 million deaths. Peripheral perfusion appears as a promising alternative target. In this sense, the excellent prognosis associated with normalization of capillary refill time, the rapid response time to fluid loading, in addition to its simplicity and availability in limited resource settings, constitute a solid background to promote studies that evaluate its usefulness for guide fluid resuscitation. Among various complementary indices, capillary refill time is a shock assessment parameter that tends to be extended in individuals with sepsis; However, this parameter is established subjectively, and its assessment lacks objectivity and reproducibility. However, if it is quantified and evaluated with an increased degree of precision, capillary refill time provides a complementary assessment of circulation, taking full advantage of the characteristics of this marker.
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Keywords
Shock Séptico, Tiempo de Llenado Capilar, Mortalidad