Características clínico-epidemiológicas de neoplasias malignas en pacientes adultos con infección por VIH
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Date
2024-02-08
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Universidad Nacional de Trujillo
Abstract
Describir las características clínico-epidemiológicas de neoplasias malignas en pacientes adultos con infección por VIH.
Materiales y método: Se realizó un estudio transversal, observacional y descriptivo; revisando historias clínicas de pacientes diagnosticados por VIH y neoplasia maligna ingresados por UCETI del HRDT desde 2005 y 2021. Se construyó la base de datos con Microsoft Excel 2019, creando dos cuadros de simple y doble entrada.
Resultados: Se recolectaron 63 historias clínicas. Características epidemiológicas: el grupo etario más afectado fue de 31 a 40 años (n=24, 38.1%). El sexo predominante fue el masculino (n=49, 77.8%); heterosexuales (n=30, 47.6%); obreros (n=14, 22.2%); solteros (n=44, 69.8%); procedentes del distrito de Trujillo (n=20, 31.7%); el consumo de tabaco, alcohol y drogas fueron 57.1% (n=36), 65.1% (n=41) y 36.5% (n=23), respectivamente. Las características clínicas: la mayoría con un IMC normal (n=37, 58.7%); diagnosticados en menos de 5 años (n=47, 74.6%); recibieron Targa (n=59, 93.7%); con recuento de linfocitos CD4 menor a 200cél/mm3 (n=32, 50.8%); una carga viral mayor a 55000copias/ml (n=23, 36.5%); el tipo de cáncer más prevalente fue el sarcoma (n=23, 36.5%).
Conclusiones: Se registra la prevalencia de pacientes con la edad entre 31 y 40 años, de sexo masculino, heterosexual, obrero, soltero, procedente del distrito de Trujillo y consumidor de alcohol y tabaco. Así como un IMC normal, el diagnóstico en menos de 5 años, la administración del Targa, recuento de CD4 menor a 200cél/mm3, carga viral mayor a 55000copias/ml, y neoplasias malignas más frecuentes como el Sarcoma Kaposi y Linfoma No Hodgkin.
ABSTRACT Objetive: To describe the clinical-epidemiological characteristics of malignant neoplasms in adult patients with HIV infection. Matherials and methods: A cross-sectional, observational and descriptive study was conducted; reviewing medical records of patients diagnosed with HIV and malignant neoplasm admitted by UCETI of the HRDT from 2005 and 2021. The database was constructed with Microsoft Excel 2019, creating two tables of single and double entry. Results: Sixty-three clinical histories were collected. Epidemiological characteristics: the most affected age group was 31 to 40 years old (n=24, 38.1%). The predominant sex was male (n=49, 77.8%); heterosexual (n=30, 47.6%); blue-collar (n=14, 22.2%); single (n=44, 69.8%); from the district of Trujillo (n=20, 31.7%); tobacco, alcohol and drug use were 57.1% (n=36), 65.1% (n=41) and 36.5% (n=23), respectively. Clinical characteristics: majority with normal BMI (n=37, 58.7%); diagnosed in less than 5 years (n=47, 74.6%); received Targa (n=59, 93.7%); with CD4 lymphocyte count less than 200cél/mm3 (n=32, 50.8%); a viral load greater than 55000copies/ml (n=23, 36.5%); the most prevalent cancer type was sarcoma (n=23, 36.5%). Conclusions: The prevalence of patients is recorded with the age between 31 and 40 years, male, heterosexual, working, single, coming from the district of Trujillo and consumer of alcohol and tobacco. As well as a normal BMI, diagnosis in less than 5 years, administration of Targa, CD4 count less than 200cél/mm3, viral load greater than 55000copies/ml, and more frequent malignant neoplasms such as Kaposi Sarcoma and Non-Hodgkin Lymphoma.
ABSTRACT Objetive: To describe the clinical-epidemiological characteristics of malignant neoplasms in adult patients with HIV infection. Matherials and methods: A cross-sectional, observational and descriptive study was conducted; reviewing medical records of patients diagnosed with HIV and malignant neoplasm admitted by UCETI of the HRDT from 2005 and 2021. The database was constructed with Microsoft Excel 2019, creating two tables of single and double entry. Results: Sixty-three clinical histories were collected. Epidemiological characteristics: the most affected age group was 31 to 40 years old (n=24, 38.1%). The predominant sex was male (n=49, 77.8%); heterosexual (n=30, 47.6%); blue-collar (n=14, 22.2%); single (n=44, 69.8%); from the district of Trujillo (n=20, 31.7%); tobacco, alcohol and drug use were 57.1% (n=36), 65.1% (n=41) and 36.5% (n=23), respectively. Clinical characteristics: majority with normal BMI (n=37, 58.7%); diagnosed in less than 5 years (n=47, 74.6%); received Targa (n=59, 93.7%); with CD4 lymphocyte count less than 200cél/mm3 (n=32, 50.8%); a viral load greater than 55000copies/ml (n=23, 36.5%); the most prevalent cancer type was sarcoma (n=23, 36.5%). Conclusions: The prevalence of patients is recorded with the age between 31 and 40 years, male, heterosexual, working, single, coming from the district of Trujillo and consumer of alcohol and tobacco. As well as a normal BMI, diagnosis in less than 5 years, administration of Targa, CD4 count less than 200cél/mm3, viral load greater than 55000copies/ml, and more frequent malignant neoplasms such as Kaposi Sarcoma and Non-Hodgkin Lymphoma.
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Keywords
Neoplasias Malignas, VIH, Monitoreo Epidemiológico