Efecto cicatrizante de un gel elaborado con el extracto etanólico de la raíz Ipomoea batatas Lam. variedad “camote amarillo” sobre lesiones dérmicas inducidas en Mus musculus “ratón albino” BALB/c.
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Date
2022
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Universidad Nacional de Trujillo
Abstract
La cicatrización de heridas es uno de los procesos más complejos del cuerpo de los animales. El objetivo fue determinar el efecto cicatrizante de un gel elaborado con el extracto etanólico de la raíz de Ipomoea batatas Lam. variedad “camote amarillo” sobre lesiones dérmicas inducidas en Mus musculus “ratón albino” BALB/c. Se colectó e identificó plantas de I. batatas; se preparó un gel con el extracto hidroalcohólico obtenido; se utilizaron quince especímenes M. musculus, los cuales se separaron en tres grupos: control (GC) con herida y sin tratamiento, control estándar (GCE) con herida y tratada con ungüento comercial y, experimental Ipomoea (GEI) con herida y tratada con gel a base de extracto de I. batatas al 0,5%; se midieron las heridas y se obtuvo el porcentaje de cicatrización; a los datos obtenidos se les aplicó la prueba ANOVA y Tukey, ambas con un 95% de confianza. Al octavo día se formaron dos grupos estadísticamente homogéneos, el “a” formado por CG (74,00 ± 4,18%) con GCE (80,00 ± 7,10%) y “b” formado por GEI (100,00 ± 0,00%). Se pudo determinar el efecto cicatrizante del gel elaborado con el extracto etanólico de la raíz de Ipomoea batatas Lam. variedad “camote amarillo” sobre lesiones dérmicas inducidas en Mus musculus “ratón albino” BALB/c. este estudio permitió observar un aumento en el porcentaje de cicatrización, lo cual indica una disminución en el tiempo de cicatrizado.
Wound healing is one of the most complex processes in the animal body. The objective was to determine the healing effect of a gel made with the ethanolic extract of the root of Ipomoea batatas Lam. variety “yellow sweet potato” on skin lesions induced in Mus musculus “albino mouse” BALB/c. Plants of I. batatas were collected and identified; a gel was prepared with the hydroalcoholic extract obtained; Fifteen M. musculus specimens were used, which were separated into three groups: control (CG) with wound and without treatment, standard control (GCE) with wound and treated with commercial ointment and, experimental Ipomoea (GEI) with wound and treated with gel based on extract of I. batatas at 0.5%; wounds were measured and the percentage of healing was obtained; The ANOVA and Tukey tests were applied to the data obtained, both with 95% confidence. On the eighth day, two statistically homogeneous groups were formed, the "a" formed by CG (74.00 ± 4.18%) with GCE (80.00 ± 7.10%) and "b" formed by GEI (100.00 ± 0.00%). The healing effect of the gel made with the ethanolic extract of the root of Ipomoea batatas Lam could be determined. variety “yellow sweet potato” on skin lesions induced in Mus musculus “albino mouse” BALB / c. This study allowed an increase in the percentage of healing to be observed, which indicates a decrease in healing time.
Wound healing is one of the most complex processes in the animal body. The objective was to determine the healing effect of a gel made with the ethanolic extract of the root of Ipomoea batatas Lam. variety “yellow sweet potato” on skin lesions induced in Mus musculus “albino mouse” BALB/c. Plants of I. batatas were collected and identified; a gel was prepared with the hydroalcoholic extract obtained; Fifteen M. musculus specimens were used, which were separated into three groups: control (CG) with wound and without treatment, standard control (GCE) with wound and treated with commercial ointment and, experimental Ipomoea (GEI) with wound and treated with gel based on extract of I. batatas at 0.5%; wounds were measured and the percentage of healing was obtained; The ANOVA and Tukey tests were applied to the data obtained, both with 95% confidence. On the eighth day, two statistically homogeneous groups were formed, the "a" formed by CG (74.00 ± 4.18%) with GCE (80.00 ± 7.10%) and "b" formed by GEI (100.00 ± 0.00%). The healing effect of the gel made with the ethanolic extract of the root of Ipomoea batatas Lam could be determined. variety “yellow sweet potato” on skin lesions induced in Mus musculus “albino mouse” BALB / c. This study allowed an increase in the percentage of healing to be observed, which indicates a decrease in healing time.
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piel de ratón, Ipomoea batatas, herida.