Infección por Staphylococcus aureus y resistencia bacteriana en pacientes atendidos en hospitales Belén y Regional de Trujillo
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Date
2025-01-08
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Universidad Nacional de Trujillo
Abstract
Determinar la frecuencia y sitios de infección por Staphylococcus aureus más frecuentes y su resistencia bacteriana, tipo de muestra aislada y lugar de procedencia de los pacientes atendidos en el Hospital Regional Docente de Trujillo (HRDT) y Hospital Belén de Trujillo (HBT) durante los años 2018 – 2022. Material y métodos: Se realizó un estudio observacional descriptivo retrospectivo, donde se recolectaron cultivos positivos para Staphylococcus aureus obtenidos de sangre, líquidos, secreciones corporales de pacientes mayores de 18 años atendidos, realizándose la revisión de historias clínicas para la extracción de las variables propuestas. Resultados: Se encontraron 336 cultivos positivos para S. aureus, con las variables en interés. A partir de la base de datos obtenida, se encontró una alta frecuencia de resistencia a Amoxicilina/Ácido Clavulánico (67.56%), mayor porcentaje (21.13%) en pacientes con Neumonía Adquirida en la Comunidad (NAC) y una mayor proporción de muestras obtenidas por hemocultivo (50.30%). Conclusión: El estudio revela una alta resistencia a la Amoxicilina/Ácido Clavulánico, mayormente encontrados en pacientes con NAC y en muestras obtenidas por hemocultivo.
Palabras clave: infección, Staphylococcus aureus, resistencia a antibióticos.
Abstract To determine the frequency and sites of the most frequent Staphylococcus aureus infection and its bacterial resistance, type of isolated sample and place of origin of patients treated at the Trujillo Regional Teaching Hospital (HRDT) and the Belén de Trujillo Hospital (HBT) during the years 2018 - 2022. Material and methods: A retrospective descriptive observational study was carried out, where positive cultures for Staphylococcus aureus were collected from blood, fluids, and body secretions of patients over 18 years of age treated, and a review of clinical records was carried out to extract the proposed variables. Results: 336 positive cultures for S. aureus were found, with the variables of interest. From the obtained database, a high frequency of resistance to Amoxicillin-clavulanic acid (67.56%) was found, a higher percentage (21.13%) in patients with Community Acquired Pneumonia (CAP) and a higher proportion of samples obtained by blood culture (50.30%). Conclusion: The study reveals a high resistance to Amoxicillin-clavulanic acid, mostly found in patients with CAP and in samples obtained by blood culture.
Abstract To determine the frequency and sites of the most frequent Staphylococcus aureus infection and its bacterial resistance, type of isolated sample and place of origin of patients treated at the Trujillo Regional Teaching Hospital (HRDT) and the Belén de Trujillo Hospital (HBT) during the years 2018 - 2022. Material and methods: A retrospective descriptive observational study was carried out, where positive cultures for Staphylococcus aureus were collected from blood, fluids, and body secretions of patients over 18 years of age treated, and a review of clinical records was carried out to extract the proposed variables. Results: 336 positive cultures for S. aureus were found, with the variables of interest. From the obtained database, a high frequency of resistance to Amoxicillin-clavulanic acid (67.56%) was found, a higher percentage (21.13%) in patients with Community Acquired Pneumonia (CAP) and a higher proportion of samples obtained by blood culture (50.30%). Conclusion: The study reveals a high resistance to Amoxicillin-clavulanic acid, mostly found in patients with CAP and in samples obtained by blood culture.
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Keywords
Infección, Estafilococo Aureus, Resistencia a Antibióticos