Uso racional de omeprazol en pacientes mayores de 60 años con polifarmacia
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Date
2025-01-23
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Universidad Nacional de Trujillo
Abstract
Los inhibidores de la bomba de protones (IBP), dentro de ellos, el Omeprazol, es ampliamente utilizado para contrarrestar los efectos del ácido clorhídrico debido a su acción en la bomba de protones de las células parietales del estómago. Sin embargo, el uso irracional de este medicamento, puede desarrollar efectos adversos nocivos para quienes no reciben una prescripción adecuada.
Objetivo: Identificar la frecuencia del uso racional de Omeprazol en pacientes mayores de 60 años con polifarmacia.
Materiales y métodos: Estudio observacional longitudinal retrospectivo donde se analizaron un total de 547 historias clínicas de pacientes ancianos con polifarmacia e indicación de omeprazol, para determinar cuántos de estos tenían una prescripción racional.
Resultados: De los 547 pacientes mayores de 60 años con polifarmacia, solo 196 (35.83%) tuvieron una indicación adecuada del medicamento, mientras que 351 (64.17%) no tenían el diagnóstico como para recibir la prescripción de Omeprazol.
Conclusiones: Se determinó que en los pacientes mayores de 60 años con polifarmacia atendidos en el hospital ESSALUD I de Florencia de Mora en el 2021, existió una prescripción no racional de Omeprazol.
Palabras clave: omeprazol, inhibidores de la bomba de protones, gastritis
Abstract Proton pump inhibitors (PPI), within them, Omeprazole, is widely used to counteract the effects of hydrochloric acid due to its action on the proton pump of the parietal cells of the stomach. However, the irrational use of this drug can develop harmful adverse effects for those who do not receive an adequate prescription. Objective: To identify the frequency of rational use of Omeprazole in patients over 60 years old with polypharmacy. Materials and methods: Retrospective longitudinal observational study in which a total of 547 medical records of patients over 60 years old with polypharmacy and indication for omeprazole were analyzed to determine how many of them had a rational prescription. Results: Of the 547 over 60 years old with polypharmacy, only 196 (35.83%) had an adequate indication of the drug, while 351 (64.17%) did not have the diagnosis as to receive the prescription of Omeprazole. Conclusions: It was determined that in patients over 60 years of age with polypharmacy treated at the ESSALUD I hospital in Florencia de Mora in 2021, there was a non-rational prescription of Omeprazole.
Abstract Proton pump inhibitors (PPI), within them, Omeprazole, is widely used to counteract the effects of hydrochloric acid due to its action on the proton pump of the parietal cells of the stomach. However, the irrational use of this drug can develop harmful adverse effects for those who do not receive an adequate prescription. Objective: To identify the frequency of rational use of Omeprazole in patients over 60 years old with polypharmacy. Materials and methods: Retrospective longitudinal observational study in which a total of 547 medical records of patients over 60 years old with polypharmacy and indication for omeprazole were analyzed to determine how many of them had a rational prescription. Results: Of the 547 over 60 years old with polypharmacy, only 196 (35.83%) had an adequate indication of the drug, while 351 (64.17%) did not have the diagnosis as to receive the prescription of Omeprazole. Conclusions: It was determined that in patients over 60 years of age with polypharmacy treated at the ESSALUD I hospital in Florencia de Mora in 2021, there was a non-rational prescription of Omeprazole.
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Keywords
Omeprazol, Inhibidores de la Bomba de Protones, Gastritis