Índice inmunidad-inflamación sistémica como predictor de apendicitis aguda complicada
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Date
2024-09-16
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Universidad Nacional de Trujillo
Abstract
Evaluar si el Índice inmunidad-inflamación sistémica es predictor de apendicitis aguda complicada. Materiales y métodos: Se recolectaron historias clínicas de 145 casos de apendicitis aguda que fueron intervenidos mediante apendicectomía en la Clínica Peruano Americana durante el periodo Enero del año 2021 al mes de Julio de 2023. Estudio observacional, transversal, retrospectivo, de tipo pruebas diagnósticas. Resultados: La cantidad pacientes con diagnóstico patológico de apendicitis aguda no complicada fue 83 (57.24%) y la cantidad de casos de apendicitis aguda complicada fue 62 (42.76%). El AUC para el Índice inmunidad-inflamación sistémica fue 0,73 (IC 95%: 0,65-0,81) con un valor p de 0,04. Usando el método de Youden, el mejor punto de corte del mencionado índice alcanzó un valor de 1758,22 (IC 95%: 1077,63-2438,81), con una sensibilidad del 86,1%, especificidad del 53,4%, valor predictivo positivo de 64.6% y valor predictivo negativo de 79.6% para el diagnóstico de apendicitis aguda complicada. Conclusión: El Índice inmunidad-inflamación sistémica es predictor de apendicitis aguda complicada.
Abstract To evaluate whether the systemic immunity-inflammation index is a predictor of complicated acute appendicitis. Materials and methods: Medical records of 145 cases of acute appendicitis that were operated on by appendectomy at Peruano Americana Clinic were collected during the period January 2021 to July 2023. Observational, cross-sectional, retrospective, diagnostic test-type study. Results: The number of patients with a pathological diagnosis of uncomplicated acute appendicitis was 83 (57.24%) and the number of cases of complicated acute appendicitis was 62 (42.76%). The AUC for the Systemic Immunity-Inflammation Index was 0.73 (95% CI: 0.65-0.81) with a p value of 0.04. Using Youden's method, the best cut-off point of the aforementioned index reached a value of 1758.22 (95% CI: 1077.63-2438.81), with a sensitivity of 86.1%, specificity of 53.4%, positive predictive value of 64.6% and negative predictive value of 79.6% for the diagnosis of complicated acute appendicitis. Conclusion: The systemic immunity-inflammation index is a predictor of complicated acute appendicitis.
Abstract To evaluate whether the systemic immunity-inflammation index is a predictor of complicated acute appendicitis. Materials and methods: Medical records of 145 cases of acute appendicitis that were operated on by appendectomy at Peruano Americana Clinic were collected during the period January 2021 to July 2023. Observational, cross-sectional, retrospective, diagnostic test-type study. Results: The number of patients with a pathological diagnosis of uncomplicated acute appendicitis was 83 (57.24%) and the number of cases of complicated acute appendicitis was 62 (42.76%). The AUC for the Systemic Immunity-Inflammation Index was 0.73 (95% CI: 0.65-0.81) with a p value of 0.04. Using Youden's method, the best cut-off point of the aforementioned index reached a value of 1758.22 (95% CI: 1077.63-2438.81), with a sensitivity of 86.1%, specificity of 53.4%, positive predictive value of 64.6% and negative predictive value of 79.6% for the diagnosis of complicated acute appendicitis. Conclusion: The systemic immunity-inflammation index is a predictor of complicated acute appendicitis.
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Keywords
Apendicitis, Neutrófilos, Linfocitos, Plaquetas