Colesterol LDL elevado como factor de riesgo para depresión en pacientes atendidos en el Hospital Distrital Santa Isabel
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Date
2023-11-16
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Universidad Nacional de Trujillo
Abstract
Los síntomas depresivos observados en los ancianos están asociados con la edad avanzada, vivir solo, ser mujer, bajo nivel educativo, divorcio, enfermedad física comórbida, trastorno funcional, consumo de alcohol y cigarrillos y disfunción cognitiva de nivel inferior; la existencia de enfermedades crónicas y la percepción de una salud baja aumentan el riesgo de depresión. Las mujeres con una alta percepción de las preocupaciones económicas, condiciones de baja funcionalidad, y la baja satisfacción con la vida, eran más depresivas .
Los perfiles de lípidos séricos, que se componen de lípidos, apolipoproteínas, transportadores de lipoproteínas, se han relacionado sistemáticamente con eventos cardiovasculares y cerebrovasculares. La evidencia abrumadora reveló las asociaciones de HDL y LDL con enfermedad coronaria y accidente cerebrovascular isquémico6. Se encontraron mujeres con niveles bajos de HDL-C una y con mayor prevalencia y riesgo de incidencia de depresión clínica, y el riesgo de persistencia a largo plazo de los síntomas se duplica cuando los niveles de HDL-C disminuyen en 0,5 mmol / L en individuos con trastorno depresivo mayor. Objetivos: Determinar si el colesterol LDL elevado es factor de riesgo para depresión en pacientes atendidos en el Hospital Distrital Santa Isabel
Metodología: cuando el interés es usar un diseño de casos y controles para determinar si el colesterol LDL elevado es factor de riesgo para la depresión . casos y controles con depresión: 93 y no depresión :93.
ABSTRACT Depressive symptoms observed in the elderly are associated with advanced age, living alone, being female, low educational level, divorce, comorbid physical illness, functional disorder, alcohol and cigarette use, and lower-level cognitive dysfunction; The existence of chronic diseases and the perception of poor health increase the risk of depression. Women with a high perception of economic worries, low functioning conditions, and low satisfaction with life were more depressed. Serum lipid profiles, which are composed of lipids, apolipoproteins, lipoprotein transporters, have been consistently linked to cardiovascular and cerebrovascular events. Overwhelming evidence revealed the associations of HDL and LDL with coronary heart disease and ischemic stroke6. Women with low HDL-C levels were found to have a higher prevalence and incidence risk of clinical depression, and the risk of long-term persistence of symptoms doubles when HDL-C levels decrease by 0.5 mmol/ L in individuals with major depressive disorder. Objectives: Determine if elevated LDL cholesterol is a risk factor for depression in patients treated at the Santa Isabel District Hospital. Methodology: when the interest is to use a case-control design to determine if elevated LDL cholesterol is a risk factor for depression. cases and controls with depression: 93 and without depression: 93.
ABSTRACT Depressive symptoms observed in the elderly are associated with advanced age, living alone, being female, low educational level, divorce, comorbid physical illness, functional disorder, alcohol and cigarette use, and lower-level cognitive dysfunction; The existence of chronic diseases and the perception of poor health increase the risk of depression. Women with a high perception of economic worries, low functioning conditions, and low satisfaction with life were more depressed. Serum lipid profiles, which are composed of lipids, apolipoproteins, lipoprotein transporters, have been consistently linked to cardiovascular and cerebrovascular events. Overwhelming evidence revealed the associations of HDL and LDL with coronary heart disease and ischemic stroke6. Women with low HDL-C levels were found to have a higher prevalence and incidence risk of clinical depression, and the risk of long-term persistence of symptoms doubles when HDL-C levels decrease by 0.5 mmol/ L in individuals with major depressive disorder. Objectives: Determine if elevated LDL cholesterol is a risk factor for depression in patients treated at the Santa Isabel District Hospital. Methodology: when the interest is to use a case-control design to determine if elevated LDL cholesterol is a risk factor for depression. cases and controls with depression: 93 and without depression: 93.
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Keywords
Colesterol LDL, Depresión, Factor de Riesgo