Evaluación de los niveles de colinesterasa sérica en agricultores del centro poblado de Mocan, Casa Grande, Ascope, La Libertad – 2022
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Date
2023
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Publisher
Universidad Nacional de Trujillo
Abstract
Se realizó la determinación de la actividad de la colinesterasa sérica en 88 muestras biológicas (73 muestras de agricultores que trabajan con plaguicidas inhibidores de la colinesterasa y 15 de un grupo de control (grupo no expuesto a los plaguicidas)) procedentes de la localidad de Mocan, distrito de Casa Grande, Ascope – La Libertad - Perú. La cuantificación de la actividad de la colinesterasa sérica se realizó empleando método de espectrofotometría cinética. Los valores promedio de los agricultores expuestos es de 56781.397 (U/L), el valor máximo oscila en 12 223 (U/L) y mínimo oscila en 3522 (U/L) de colinesterasa sérica mismo que se halla por debajo del valor crítico establecido: 5320 (U/L) – 12920 (U/L). De igual manera en el grupo de agricultores expuestos se muestra que las medidas de dispersión reflejan, en general, que los datos tienden a la homogeneidad (CV < 20%); con excepción de algunos valores del grado de instrucción (en ambos sexos) y el total de la muestra, cuyo CV tiende a ser mayor al 20%. Vale resaltar que, la edad se correlaciona fuerte y positivamente con el tiempo de exposición a plaguicidas, tal como lo confirma el coeficiente de determinación de Pearson (R2 = 93.32%) y de Spearman (R2 = 93.70%).
The determination of serum cholinesterase activity was carried out in 88 biological samples (73 samples from farmers who work with cholinesterase inhibitor pesticides and 15 from a control group (group not exposed to pesticides)) from the town of Mocan. Casa Grande district, Ascope – La Libertad - Peru. Quantification of serum cholinesterase activity was performed using the kinetic spectrophotometry method. The average values of the exposed farmers are 56,781,397 (U/L), the maximum value ranges from 12,223 (U/L) and the minimum ranges from 3,522 (U/L) of serum cholinesterase, which is below the critical value. set: 5320 (U/L) – 12920 (U/L). Similarly, in the group of exposed farmers it is shown that the dispersion measures reflect, in general, that the data tend towards homogeneity (CV < 20%); with the exception of some values of the level of education (in both sexes) and the total sample, whose CV tends to be greater than 20%. It is worth highlighting that age correlates strongly and positively with the time of exposure to pesticides, as confirmed by the Pearson (R2 = 93.32%) and Spearman (R2 = 93.70%) coefficient of determination.
The determination of serum cholinesterase activity was carried out in 88 biological samples (73 samples from farmers who work with cholinesterase inhibitor pesticides and 15 from a control group (group not exposed to pesticides)) from the town of Mocan. Casa Grande district, Ascope – La Libertad - Peru. Quantification of serum cholinesterase activity was performed using the kinetic spectrophotometry method. The average values of the exposed farmers are 56,781,397 (U/L), the maximum value ranges from 12,223 (U/L) and the minimum ranges from 3,522 (U/L) of serum cholinesterase, which is below the critical value. set: 5320 (U/L) – 12920 (U/L). Similarly, in the group of exposed farmers it is shown that the dispersion measures reflect, in general, that the data tend towards homogeneity (CV < 20%); with the exception of some values of the level of education (in both sexes) and the total sample, whose CV tends to be greater than 20%. It is worth highlighting that age correlates strongly and positively with the time of exposure to pesticides, as confirmed by the Pearson (R2 = 93.32%) and Spearman (R2 = 93.70%) coefficient of determination.
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Keywords
Plaguicidas , Espectofotometria cinética