Asmat Anhuamán, Ana MariselaValderrama Alarco, Yosep Segundo6/28/20236/28/20232019-05-02https://hdl.handle.net/20.500.14414/18205To determine whether the use of oral contraceptives is a protective factor for the development of rheumatoid arthritis in adult women treated at the Trujillo Regional Teaching Hospital.Material and methods: As it was a retrospective study, secondary sources were used, through the use of medical records, which are found in the statistics file of the referred hospital. For which the electronic registry of female patients with rheumatoid arthritis was requested, said information is registered in the Her Mis system. For which the corresponding permission was requested to carry out the study in the aforementioned Hospital, sending a request addressed to the director for her attention. Once the database of the aforementioned program has been reviewed. The woman with rheumatoid arthritis was located, making a list, verifying that they met the selection criteria until completing the sample size, considering four controls for each case. In the same way, the control group was selected. Once the sampling is done, the data was transcribed to the data collection sheet prepared for this purpose. The file consists of three parts, the first collects general data, the second part collects data on the study dependent variables, which is the presence or absence of rheumatoid arthritis. The third part collects information about the use of the oral hormonal contraceptive. The variables were studied: rheumatoid arthritis and use of oral contraceptives. Within the analysis and interpretation of the information, the information processing was carried out using a computer that contains the statistical package IBM SPSS version 23.0. The absolute and relative frequencies (percentages) were taken into account, shown in tetrachoric tables according to the specific objectives proposed in this study. For the analysis, the Chi square statistical test was applied to determine the relationship through the association or independence of the variables under study, considering p <0.05 as significant and p <0.01 highly significant. Likewise, the Odds ratio association test was applied, with its 95% confidence interval. To carry out the project, the international recommendations established in the Declaration of Helsinki II were taken into account, which has as a basic principle that the research that It involves human beings must be conducted only by scientifically qualified persons and under the supervision of a doctor, taking into account the publication, the doctor is obliged to preserve its veracity, maintaining the anonymity of the investigated patients at all times. 01 highly significant. Likewise, the Odds ratio association test was applied, with its 95% confidence interval. To carry out the project, the international recommendations established in the Declaration of Helsinki II were taken into account, which has as a basic principle that the research that It involves human beings must be conducted only by scientifically qualified persons and under the supervision of a doctor, taking into account the publication, the doctor is obliged to preserve its veracity, maintaining the anonymity of the investigated patients at all times. 01 highly significant. Likewise, the Odds ratio association test was applied, with its 95% confidence interval. To carry out the project, the international recommendations established in the Declaration of Helsinki II were taken into account, which has as a basic principle that the research that It involves human beings must be conducted only by scientifically qualified persons and under the supervision of a doctor, taking into account the publication, the doctor is obliged to preserve its veracity, maintaining the anonymity of the investigated patients at all times.Determinar si el uso de anticonceptivos orales es un factor protector para el desarrollo de la artritis reumatoide en mujeres adultas atendidas en el Hospital Regional Docente de Trujillo Material y métodos: Por ser un estudio retrospectivo se usó fuentes secundarias, mediante el uso de historias clínicas las mismas que se encuentran en el archivo de estadística del referido hospital. Para lo cual se solicitó el registro electrónico de pacientes mujeres con artritis reumatoide, dicha información está registrada en el sitema His Mis. Para lo cual se solicitó el permiso correspondiente para realizar el estudio en el referido Hospital enviándose una solicitud dirigida al director para su atención. Una vez revisada la base de datos del referido programa. Se ubicó a la mujer con artritis reumatoide, realizando un listado, verificando que cumplan los criterios de selección hasta completar el tamaño muestral, considerando por cada caso cuatro controles. De la misma forma se seleccionó el grupo control. Una vez realizada el muestreo, se procedió a transcribir los datos a la ficha de recolección de datos elaborada para dicho fin. La ficha consta de tres partes, la primera recolecta los datos generales la segunda parte recolecta datos sobre las variables dependiente de estudio que es la presencia o no de artritis reumatoide. La tercera parte recoge información acerca del uso del anticonceptivo hormonal oral. Se estudiaron las variables: artritis reumatoide y uso de anticonceptivos orales. Dentro del análisis y interpretación de la información, el procesamiento de la información se realizó usando una computadora que contenga el paquete estadístico IBM SPSS versión 23.0. Se tomó en cuenta las frecuencias absolutas y relativas (porcentajes), plasmados en tablas tetracóricas de acuerdo a los objetivos específicos propuestos en el presente estudio. Para el análisis se aplicó la prueba estadística del Chi cuadrado para determinar la relación mediante la asociación o independencia de las variables en estudio, considerándose p<0,05 como significativo y p<0.01 altamente significativo. Así mismo se aplicó la prueba de asociación de Odds ratio, con su intervalo de confianza al 95%.Para la realización del proyecto se tomó en cuenta las recomendaciones internacionales dispuestas en la Declaración de Helsinki II, que tiene como principio básico que la investigación que involucre seres humanos debe ser conducida sólo por personas científicamente calificadas y bajo la supervisión de un médico, teniendo en cuenta la publicación, el médico está obligado a preservar su veracidad, manteniendo en todo momento en el anonimato de los pacientes investigados.spainfo:eu-repo/semantics/openAccessArtritis ReumatoideAnticonceptivos oralesReumatismo polindromicosinfo:eu-repo/semantics/monograph