Propofol asociado a terapia estándar en náuseas y vómitos postoperatorios en pacientes colecistectomizados
No Thumbnail Available
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Nacional de Trujillo
Abstract
Las náuseas y vómitos postoperatorios ocurren frecuentemente en el contexto perioperatorio, en este sentido la identificación de estrategias para la profilaxis de este evento adverso es relevante para la prevención de complicaciones. El presente proyecto de investigación plantea demostrar que el Propofol asociado a terapia estándar es efectivo en la prevención en náuseas y vómitos postoperatorios en pacientes colecistectomizados del Hospital Regional Docente de Trujillo durante el periodo noviembre 2022 – Abril 2023. Se obtendrá el consentimiento informado de los pacientes que ingresen al estudio. La muestra estará conformada por 56 pacientes intervenidos bajo anestesia general para cada grupo. Grupo 1: Propofol a dosis de 0.5 mg/kg al término de la cirugía más terapia estándar. Grupo 2: Terapia estándar. Se registrará la frecuencia de náuseas y vómitos en el postoperatorio inmediato cada hora durante las primeras 24 horas. La información obtenida será registrada en hojas de recolección de datos y procesados usando el programa estadístico SPSS V.25. Para determinar qué tratamiento es más eficaz, se aplicará la Prueba Chi Cuadrado para diferencia de proporciones. Si P< 0,05 existirá diferencia significativa de la presencia de náuseas y vómitos postoperatorios entre los pacientes con los tratamientos aplicados.
Postoperative nausea and vomiting frequently occur in the perioperative context, in this sense the identification of strategies for the prophylaxis of this adverse event is relevant for the prevention of complications. The present research project aims to demonstrate that Propofol associated with standard therapy is effective in preventing postoperative nausea and vomiting in cholecystectomized patients at the Trujillo Regional Teaching Hospital during the period November 2022 – April 2023. Informed consent will be obtained from the patients. to enter the study. The sample will consist of 56 patients operated on under general anesthesia for each group. Group 1: Propofol at a dose of 0.5 mg/kg at the end of surgery plus standard therapy. Group 2: Standard therapy. The frequency of nausea and vomiting in the immediate postoperative period will be recorded every hour for the first 24 hours. The information obtained will be recorded on data collection sheets and processed using the SPSS V.25 statistical program. To determine which treatment is more effective, the Chi Square Test will be applied for difference in proportions. If P < 0.05, there will be a significant difference in the presence of postoperative nausea and vomiting between patients with the treatments applied.
Postoperative nausea and vomiting frequently occur in the perioperative context, in this sense the identification of strategies for the prophylaxis of this adverse event is relevant for the prevention of complications. The present research project aims to demonstrate that Propofol associated with standard therapy is effective in preventing postoperative nausea and vomiting in cholecystectomized patients at the Trujillo Regional Teaching Hospital during the period November 2022 – April 2023. Informed consent will be obtained from the patients. to enter the study. The sample will consist of 56 patients operated on under general anesthesia for each group. Group 1: Propofol at a dose of 0.5 mg/kg at the end of surgery plus standard therapy. Group 2: Standard therapy. The frequency of nausea and vomiting in the immediate postoperative period will be recorded every hour for the first 24 hours. The information obtained will be recorded on data collection sheets and processed using the SPSS V.25 statistical program. To determine which treatment is more effective, the Chi Square Test will be applied for difference in proportions. If P < 0.05, there will be a significant difference in the presence of postoperative nausea and vomiting between patients with the treatments applied.
Description
Keywords
Náuseas , Agentes anestésicos, Vómitos