Detección de β-lactamasas de espectro extendido en Escherichia coli aisladas de urocultivos en el Hospital Santa Isabel - Trujillo, 2021
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Date
2024
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Universidad Nacional de Trujillo
Abstract
La infección del tracto urinario (ITU) es originada frecuentemente por E. coli, y su
tratamiento mediante el uso de antibióticos es amenazado por la presencia de cultivos
bacterianos productores de β - lactamasas de espectro extendido (BLEE). El objetivo de esta
investigación fue la detección fenotípica de BLEE en E. coli aisladas de urocultivos en el
Hospital Santa Isabel del distrito de Trujillo – Perú, entre marzo y octubre del 2021. Se aplicó
un estudio de tipo descriptivo experimental de corte transversal. Se tomaron registros de 352
cultivos de orina, de los cuales 70 cultivos fueron positivas a E. coli y se realizó la detección
fenotípica de BLEE mediante el método de confirmación de Jarlier. La frecuencia de cultivos
de E. coli productoras de BLEE fue del 32,85%. En conclusión, se detectó fenotípicamente
BLEE en 32.85% de cultivos de E. coli aisladas de urocultivos en el Hospital distrital Santa
Isabel en el distrito de Trujillo–La Libertad, entre marzo a octubre del 2021.
Urinary tract infection (UTI) is frequently caused by E. coli, and its treatment through the use of antibiotics is threatened by the presence of bacterial cultures producing extendedspectrum β-lactamases (ESBL). The objective of this research was the phenotypic detection of ESBL in E. coli isolated from urine cultures at the Santa Isabel Hospital in the district of Trujillo - Peru, between March and October 2021. A cross-sectional experimental descriptive study was applied. Records of 352 urine cultures were taken, of which 70 cultures were positive for E. coli and the identification and phenotypic detection of ESBL were carried out using the Jarlier confirmation method. The frequency of ESBL-producing E. coli cultures was 32.85%. In conclusion, it was determined that the phenotypic detection of extended spectrum β-lactamases in E.coli isolated from urine cultures at the Santa Isabel District Hospital in the Trujillo–La Libertad district, between March and October 2021, was 32.85%.
Urinary tract infection (UTI) is frequently caused by E. coli, and its treatment through the use of antibiotics is threatened by the presence of bacterial cultures producing extendedspectrum β-lactamases (ESBL). The objective of this research was the phenotypic detection of ESBL in E. coli isolated from urine cultures at the Santa Isabel Hospital in the district of Trujillo - Peru, between March and October 2021. A cross-sectional experimental descriptive study was applied. Records of 352 urine cultures were taken, of which 70 cultures were positive for E. coli and the identification and phenotypic detection of ESBL were carried out using the Jarlier confirmation method. The frequency of ESBL-producing E. coli cultures was 32.85%. In conclusion, it was determined that the phenotypic detection of extended spectrum β-lactamases in E.coli isolated from urine cultures at the Santa Isabel District Hospital in the Trujillo–La Libertad district, between March and October 2021, was 32.85%.
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