Monitoreo Microbiológico del aire y superficies de un Laboratorio Farmacéutico Nacional
| dc.contributor.advisor | Ganoza Gasco, Frizzi Judith | |
| dc.contributor.author | Varas Arribasplata, Veronica Liliana | |
| dc.date.accessioned | 2023-11-13T13:59:34Z | |
| dc.date.available | 2023-11-13T13:59:34Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Los monitoreos microbiológicos ambientales y de superficies son controles rutinarios, estrictos que se realizan continuamente en los diversos laboratorios farmacéuticos, debido a que estos están en contacto de manera directa e indirecta con los diversos productos que se manufacturen. El objetivo principal de este estudio fue realizar el monitoreo microbiológico del aire y superficies de un Laboratorio Farmacéutico Nacional. En total se seleccionaron 31 puntos de muestreo ambiental para el análisis de bacterias mesófilas aerobias, hongos y levaduras, 27 puntos de muestreo de superficie de ambientes para el análisis de bacterias mesófilas aerobias, hongos y levaduras, y 31 puntos de muestreo de superficies para el análisis de bacterias mesófilas aerobias, hongos y levaduras. Los resultados no evidenciaron contaminación, con recuentos bajos en bacterias mesófilas aerobias encontrándose dentro del límite permisible, y con respecto a los recuentos de hongos y levaduras se evidencio ausencia. Además, se evidenció que la limpieza constante y aplicación de la rotación de sanitizantes en las diferentes áreas, es un buen instrumento para minimizar los recuentos de bacterias en superficies. Se concluye que el monitoreo microbiológico, es óptimo en las diversas áreas de manufactura. | |
| dc.description.abstract | ABSTRACT The microbiological environmental and surface monitoring are routine, strict controls that are carried out continuously in the various pharmaceutical laboratories, because they are in direct and indirect contact with the various products that are manufactured. The main objective of this study was to carry out the microbiological monitoring of the air and surfaces of a National Pharmaceutical Laboratory. In total, 31 environmental sampling points were selected for the analysis of aerobic mesophilic bacteria, fungi and yeasts, 27 environmental surface sampling points for the analysis of aerobic mesophilic bacteria, fungi and yeasts, and 31 surface sampling points for the analysis of aerobic mesophilic bacteria, fungi and yeasts. The results did not show contamination, with low counts in aerobic mesophilic bacteria being within the permissible limit, and with respect to the counts of fungi and yeasts, absence was evident. In addition, it was evidenced that constant cleaning and application of the rotation of sanitizers in the different areas is a good instrument to minimize the counts of bacteria on surfaces. It is concluded that microbiological monitoring is optimal in the various manufacturing areas. | |
| dc.format | application/pdf | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14414/19484 | |
| dc.language.iso | es | |
| dc.publisher | Universidad Nacional de Trujillo | |
| dc.publisher.country | PE | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.source | Universidad Nacional de Trujillo | |
| dc.source | Repositorio Institucional UNITRU | |
| dc.subject | Monitoreo microbiológico, bacterias mesófilas aerobias, hongos y levaduras, limpieza y sanitizante. | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.01.05 | |
| dc.title | Monitoreo Microbiológico del aire y superficies de un Laboratorio Farmacéutico Nacional | |
| dc.type | info:eu-repo/semantics/bachelorThesis | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| renati.advisor.dni | 4 1294266 | |
| renati.advisor.orcid | https://orcid.org/0000-0001-8259-4161 | |
| renati.author.dni | 7 6745508 | |
| renati.discipline | 917046 | |
| renati.juror | Alva Plasencia, Pedro Marcelo | |
| renati.juror | Ganoza Gasco, Frizzi Judith | |
| renati.juror | Saldaña Bobadilla, Vanessa | |
| renati.level | http://purl.org/pe-repo/renati/level#tituloProfesional | |
| renati.type | http://purl.org/pe-repo/renati/type#tesis | |
| thesis.degree.discipline | Farmacia | |
| thesis.degree.grantor | Universidad Nacional de Trujillo. Facultad de Farmacia y Bioquímica | |
| thesis.degree.name | Químico Farmacéutico |