Relación entre el índice digital 2D:4D y la severidad del acné vulgar en mujeres en un hospital regional del norte del Perú durante los meses enero – junio de 2021
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Date
2022-05-17
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Universidad Nacional de Trujillo
Abstract
El acné vulgar es una patología muy frecuente, su prevalencia se estima entre el 70 y 87% de la población adolescente, llegando incluso hasta el 95% en algunas poblaciones. Se produce por la interacción de diversos factores patogénicos como la colonización por C. acnes, queratinización anómala, influencia androgénica e inflamación. Clínicamente se caracteriza por la aparición de lesiones inflamatorias y no inflamatorias, y su clasificación se basa en función de estas y de su extensión, llegando a provocar gran comorbilidad, no solo física, si no psicológica, especialmente en los adolescentes, los cuales son el principal grupo etario en el cual se produce la enfermedad. Por otro lado, se ha encontrado que existe una relación negativa entre la presencia de acné vulgar y el índice digital 2D:4D y una relación positiva entre dicho índice y la severidad. Es por ello, que el índice digital 2D:4D al ser fácilmente calculable podría ser un indicador o factor de riesgo para la severidad del acné vulgar que motivaría a tener un control más estricto y/o iniciar un tratamiento más agresivo de forma más temprana, para disminuir las comorbilidades y secuelas.
Abstract Acne vulgaris is a very frequent pathology, its prevalence is estimated between 70 and 87% of the adolescent population, even reaching 95% in some populations. It is produced by the interaction of various pathogenic factors such as colonization by C. acnes, abnormal keratinization, androgenic influence and inflammation. Clinically, it is characterized by the appearance of inflammatory and non-inflammatory lesions, and its classification is based on these and their extension, causing great comorbidity, not only physical, but also psychological, especially in adolescents, who are the main age group in which the disease occurs. On the other hand, it has been found that there is a negative relationship between the presence of acne vulgaris and the 2D:4D digital ratio and a positive relationship between said index and severity. For this reason, the 2D:4D digital ratio, being easily calculable, could be an indicator or risk factor for the severity of acne vulgaris that would motivate stricter control and/or start more aggressive treatment earlier. to reduce comorbidities and sequelae.
Abstract Acne vulgaris is a very frequent pathology, its prevalence is estimated between 70 and 87% of the adolescent population, even reaching 95% in some populations. It is produced by the interaction of various pathogenic factors such as colonization by C. acnes, abnormal keratinization, androgenic influence and inflammation. Clinically, it is characterized by the appearance of inflammatory and non-inflammatory lesions, and its classification is based on these and their extension, causing great comorbidity, not only physical, but also psychological, especially in adolescents, who are the main age group in which the disease occurs. On the other hand, it has been found that there is a negative relationship between the presence of acne vulgaris and the 2D:4D digital ratio and a positive relationship between said index and severity. For this reason, the 2D:4D digital ratio, being easily calculable, could be an indicator or risk factor for the severity of acne vulgaris that would motivate stricter control and/or start more aggressive treatment earlier. to reduce comorbidities and sequelae.
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Keywords
Acné vulgar, Índice digital 2D:4D, Severidad