Correlación entre biomarcadores hematológicos y proteína c reactiva en pacientes sospechosos COVID-19 atendidos en un policlínico de Lima metropolitana. 2020-2021
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Date
2023
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Universidad Nacional de Trujillo
Abstract
El presente estudio de investigación busco determinar la correlación entre los biomarcadores hematológicos y la proteína C reactiva en pacientes sospechosos COVID-19 atendidos en un policlínico de Lima Metropolitana, 2020-2021. Se utilizó una metodología de tipo observacional, retrospectivo y correlacional, se incluyeron a 130 pacientes sospechosos COVID-19, luego la obtención datos se realizó mediante la revisión documental y una ficha de recolección de datos, estructurada como datos generales, biomarcadores hematológicos y proteína C reactiva. Asimismo, se empleó la prueba estadística de correlación Rho de Spearman. Los resultados evidenciaron que la edad promedio de los pacientes sospechosos COVID-19 fue de 55.36 años, tendiendo el 55.4% una edad mayor o igual a 55 años, el 51.5% fueron del sexo femenino. Además, se observó una correlación significativa directa entre la proteína C reactiva y el recuento diferencia basófilos (p=0.013, Rho =0.218) y segmentados (p=0.006, Rho=0.240). En cambio, fue de manera inversa eosinófilos (p=0.001, Rho=-0.281), linfocitos (p=-0.401, Rho=0.000). Respecto al ancho de distribución la relación directa fue eritrocitaria (p=0.008, Rho=0.232) y las inversas fueron el volumen corpuscular (p=0.003, Rho=-0.259) y hemoglobina corpuscular media (p=0.023, Rho=- 0.200). Se concluye que, a mayor o menor nivel de resultado en biomarcadores
hematológicos, mayor o menor es el nivel de proteína C reactiva, como también, a mayor nivel de resultado de biomarcadores hematológicos menor el nivel de proteína C reactiva y viceversa en pacientes sospechosos COVID-19.
The present research study sought to determine the correlation between hematological biomarkers and C-reactive protein in suspected COVID-19 patients treated at a polyclinic in Metropolitan Lima, 2020-2021. An observational, retrospective and correlational methodology was used, 130 suspected COVID-19 patients were included, then data was obtained through documentary review and a data collection sheet, structured as general data, hematological biomarkers and protein C. reactive. Likewise, Spearman's Rho statistical correlation test was used. The results showed that the average age of the suspected COVID- 19 patients was 55.36 years, with 55.4% tending to be older than or equal to 55 years, 51.5% were female. In addition, a direct significant correlation was observed between C-reactive protein and basophil (p=0.013, Rho =0.218) and segmented (p=0.006, Rho=0.240) count difference. Instead, it was inversely eosinophils (p=0.001, Rho=-0.281), lymphocytes (p=- 0.401, Rho=0.000). Regarding distribution width, the direct relationship was erythrocyte (p=0.008, Rho=0.232) and the inverse were corpuscular volume (p=0.003, Rho=-0.259) and mean corpuscular hemoglobin (p=0.023, Rho=-0.200). . It is concluded that, the higher or lower level of result in hematological biomarkers, the higher or lower the level of C-reactive protein, as well as, the higher the level of result of hematological biomarkers, the lower the level of C-reactive protein and vice versa in suspected COVID patients. -19.
The present research study sought to determine the correlation between hematological biomarkers and C-reactive protein in suspected COVID-19 patients treated at a polyclinic in Metropolitan Lima, 2020-2021. An observational, retrospective and correlational methodology was used, 130 suspected COVID-19 patients were included, then data was obtained through documentary review and a data collection sheet, structured as general data, hematological biomarkers and protein C. reactive. Likewise, Spearman's Rho statistical correlation test was used. The results showed that the average age of the suspected COVID- 19 patients was 55.36 years, with 55.4% tending to be older than or equal to 55 years, 51.5% were female. In addition, a direct significant correlation was observed between C-reactive protein and basophil (p=0.013, Rho =0.218) and segmented (p=0.006, Rho=0.240) count difference. Instead, it was inversely eosinophils (p=0.001, Rho=-0.281), lymphocytes (p=- 0.401, Rho=0.000). Regarding distribution width, the direct relationship was erythrocyte (p=0.008, Rho=0.232) and the inverse were corpuscular volume (p=0.003, Rho=-0.259) and mean corpuscular hemoglobin (p=0.023, Rho=-0.200). . It is concluded that, the higher or lower level of result in hematological biomarkers, the higher or lower the level of C-reactive protein, as well as, the higher the level of result of hematological biomarkers, the lower the level of C-reactive protein and vice versa in suspected COVID patients. -19.
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Keywords
Biomarcador hematológico, Proteína C reactiva, COVID-19