Factores de riesgo asociados a la mortalidad en pacientes con COVID-19 ingresados a UCI

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dc.contributor.advisorRodríguez Benites, Arnold Frank
dc.contributor.authorGarcía Floriano, Lesli Alexandra
dc.contributor.authorSilva Tamayo, Leslie Juliss
dc.date.accessioned2023-03-29T15:31:02Z
dc.date.available2023-03-29T15:31:02Z
dc.date.issued2023-03-14
dc.descriptionTo determine the factors associated with mortality in patients with COVID-19 admitted to the intensive care unit through a systematic search in databases published between March 2020 and December 2021. Methods: Systematic review and meta-analysis. The risk of bias was assessed using the Newcastle-Ottawa scale and the OR was calculated using the EPIDAT 3.1 program to evaluate the association of risk factors with mortality. Results: Variables are reported with pooled OR and 95% CI, 33 studies (27,075 patients) were included in the review. Male sex (OR 1.18, 95% CI, 1.07-1.31), smoking (OR 1.44, 95% CI, 1.22-1.70), Diabetes (OR 1.48, 95% CI % % 95%, 1.35-1.63), ICC (OR 1.54, 95% CI, 1.09-2.19), BPH (OR 1.63, 95% CI, 1.48-1 .80), COPD (OR 1.70, 95% CI, 1.44-2.0), Cancer (OR 1.96, 95% CI, 1.70-2.26), CKD (OR 2.06, 95% CI, 1.61-2.63), CVD (OR 2.34, 95% CI, 1.58-3.45) were associated with mortality. Conclusions: Pre-existing comorbidities and characteristics such as age or previous exposure to tobacco were associated with mortality; These factors have prognostic relevance for patients admitted to intensive care with COVID-19.es_PE
dc.description.abstractDeterminar los factores asociados a mortalidad en pacientes con COVID – 19 ingresados en unidad de cuidados intensivos mediante una búsqueda sistemática de bases de datos publicados entre marzo de 2020 y diciembre de 2021. Métodos: Revisión sistemática y metaanálisis. Se evaluó el riesgo de sesgo con la escala de Newcastle-Ottawa y se calculó el OR mediante el programa EPIDAT 3.1 para valorar la asociación de los factores de riesgo con la mortalidad. Resultado: Las variables se informaron con OR agrupado e IC del 95 %, se incluyeron 33 estudios (27 075 pacientes) en la revisión. El sexo masculino (OR 1.18, IC 95%, 1.07-1.31), tabaquismo (OR 1.44, IC 95%, 1.22-1.70), Diabetes (OR 1.48, IC 95%, 1.35-1.63), ICC (OR 1.54, IC 95%, 1.09-2.19), HTA (OR 1.63, IC 95%, 1.48-1.80), EPOC (OR 1.70, IC 95%, 1.44-2.0), Cáncer (OR 1.96, IC 95%, 1.70-2.26), ERC (OR 2.06, IC 95%, 1.61-2.63) y ECV (OR 2.34, IC 95%, 1.58-3.45) se asociaron con la mortalidad. Conclusión: Las comorbilidades preexistentes y características como edad o exposición anterior al tabaco se asociaron con la mortalidad; estos factores tienen relevancia pronóstica para los pacientes ingresados en cuidados intensivos con COVID-19.es_PE
dc.description.uriTesises_PE
dc.identifier.urihttps://hdl.handle.net/20.500.14414/16357
dc.language.isospaes_PE
dc.publisherUniversidad Nacional de Trujilloes_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_PE
dc.sourceUniversidad Nacional de Trujilloes_PE
dc.sourceRepositorio institucional - UNITRUes_PE
dc.subjectFactores de riesgoes_PE
dc.subjectMortalidades_PE
dc.subjectUCIes_PE
dc.subjectPacientes críticoses_PE
dc.subjectCOVID-19es_PE
dc.titleFactores de riesgo asociados a la mortalidad en pacientes con COVID-19 ingresados a UCIes_PE
dc.typeinfo:eu-repo/semantics/bachelorThesises_PE
renati.advisor.dni40681722
renati.advisor.orcidhttps://orcid.org/0000-0003-4221-398X
renati.author.dni75666655
renati.author.dni47833561
renati.discipline912016
renati.jurorAbanto Montalván, Percy
renati.jurorEvangelista Montoya, Félix Alberto
renati.jurorGonzález Moreno, Juan Manuel
thesis.degree.disciplineMedicinaes_PE
thesis.degree.grantorUniversidad Nacional de Trujillo.Facultad de Medicinaes_PE
thesis.degree.levelTítulo Profesionales_PE
thesis.degree.nameMédico Cirujanoes_PE
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