Grupo sanguíneo A y riesgo de falla respiratoria en pacientes con COVID-19 en Trujillo
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Date
2024-02-13
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Universidad Nacional de Trujillo
Abstract
Evaluar si el grupo sanguíneo A es un factor de riesgo para desarrollar falla respiratoria en pacientes con COVID-19.
Método: Estudio analítico, observacional y longitudinal, de tipo cohorte histórica. Se registraron 405 historias clínicas de pacientes hospitalizados diagnosticados con COVID-19 entre 18 a 65 años, sin comorbilidades y, con su grupo sanguíneo y AGA registrado. La falla respiratoria se describió como PaO2 menor a 60 mmHg con o sin hipercapnea (PaCO2 mayor a 45 mmHg) a FiO2 21%.
Resultados: Del total de la muestra, 219 pacientes (54.10 %) hicieron falla respiratoria, mientras que los otros 188 pacientes (45.90 %), no, siendo los hombres los más afectados (63.93 %). El riesgo de desarrollar falla respiratoria con el grupo sanguíneo A fue del 56.72 %; y en aquellos con grupo sanguíneo no A fue del 53.55 %. El riesgo relativo fue de 1.0591 (IC 90% 0.8726 – 1.2856).
Conclusiones: El grupo sanguíneo A es un factor de riesgo para desarrollar falla respiratoria en la muestra estudiada entre abril 2020 y abril 2021. No se encuentra asociación de las variables para la población. Se requieren más estudios en nuestro país y continente.
Abstract To evaluate whether blood group A is a risk factor for developing respiratory failure in patients with COVID-19. Method: Analytical, observational and longitudinal study, historical cohort type. 405 medical records were recorded of hospitalized patients diagnosed with COVID-19 between 18 and 65 years old, without comorbidities and with their blood group and blood gas test recorded. Respiratory failure was described as PaO2 less than 60 mmHg with or without hypercapnea (PaCO2 greater than 45 mmHg) at FiO2 21%. Results: 219 patients (54.10%) had respiratory failure, while the other 188 patients (45.90%) did not, with men being the most affected (63.93%). The risk of developing respiratory failure with blood group A was 56.72%; and in those with blood group no A it was 53.55%. The relative risk was 1.0591 (90% CI 0.8726 – 1.2856). Conclusions: Blood group A is a risk factor for developing respiratory failure in the sample studied between April 2020 and April 2021. No association of the variables is found for the population. More studies are required in our country and continent.
Abstract To evaluate whether blood group A is a risk factor for developing respiratory failure in patients with COVID-19. Method: Analytical, observational and longitudinal study, historical cohort type. 405 medical records were recorded of hospitalized patients diagnosed with COVID-19 between 18 and 65 years old, without comorbidities and with their blood group and blood gas test recorded. Respiratory failure was described as PaO2 less than 60 mmHg with or without hypercapnea (PaCO2 greater than 45 mmHg) at FiO2 21%. Results: 219 patients (54.10%) had respiratory failure, while the other 188 patients (45.90%) did not, with men being the most affected (63.93%). The risk of developing respiratory failure with blood group A was 56.72%; and in those with blood group no A it was 53.55%. The relative risk was 1.0591 (90% CI 0.8726 – 1.2856). Conclusions: Blood group A is a risk factor for developing respiratory failure in the sample studied between April 2020 and April 2021. No association of the variables is found for the population. More studies are required in our country and continent.
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Keywords
COVID-19, Grupos Sanguíneos ABO, Insuficiencia Respiratoria