Factores predictores de apendicitis complicada en pacientes pediátricos
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Date
2025-01-10
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Universidad Nacional de Trujillo
Abstract
Determinar si la leucocitosis, neutrofilia, porcentaje de neutrófilos aumentado, INL aumentado, IPL aumentado, duración prolongada de los síntomas, tiempo prequirúrgico prolongado y edad menor a 5 años son factores predictores de apendicitis complicada en pacientes pediátricos.
Materiales y métodos: Se realizó un estudio retrospectivo tipo casos y controles, en 189 pacientes < 18 años post-operados por apendicitis aguda entre 2015-2019 en dos hospitales. Se realizó un análisis bivariado y multivariado de los factores predictores de interés entre pacientes con apendicitis aguda complicada y no complicada.
Resultados: De 189 pacientes incluidos, 126 (66,67%) fueron apendicitis no complicada y 63 (33,33%) apendicitis complicada. El análisis bivariado mostró que los neutrófilos >10100 [OR = 2,12 (IC 95%: 1-4,50), p = 0,047), la duración de los síntomas >72 horas [OR = 3,12 (IC 95%: 1,19-8,21), p = 0,017] presentaron una asociación significativa, mientras que el análisis multivariado confirmó que la duración de los síntomas (OR = 3,064; IC del 95% = 1,152 - 8,151; P = 0,025) fue un predictor independiente de apendicitis aguda complicada.
Conclusiones: La duración de los síntomas >72 horas y neutrófilos >10100 son factores predictores de apendicitis aguda complicada en pacientes pediátricos.
Palabras clave: Apendicitis, Pediatría, Neutrófilos
Abstract To determine whether leukocytosis, neutrophilia, increased neutrophil percentage, increased INL, increased IPL, prolonged duration of symptoms, prolonged preoperative time and age less than 5 years are predictors of complicated appendicitis in pediatric patients. Materials and Methods: A retrospective case-control study was performed in 189 patients < 18 years post-operated for acute appendicitis between 2015-2019 in two hospitals. A bivariate and multivariate analysis of predictor factors of interest between patients with complicated and uncomplicated acute appendicitis was performed. Results: Of 189 patients included, 126 (66.67%) were uncomplicated appendicitis and 63 (33.33%) were complicated appendicitis. Bivariate analysis showed that neutrophils >10100 [OR = 2.12 (95% CI: 1-4.50), p = 0.047), symptom duration >72 hours [OR = 3.12 (95% CI: 1.19-8.21), P = 0.017] presented a significant association, while multivariate analysis confirmed that symptom duration (OR = 3.064, 95% CI = 1.152 - 8.151, P = 0.025) was an independent predictor of complicated acute appendicitis. Conclusions: Duration of symptoms >72 hours and neutrophils >10100 are predictors of complicated acute appendicitis in pediatric patients.
Abstract To determine whether leukocytosis, neutrophilia, increased neutrophil percentage, increased INL, increased IPL, prolonged duration of symptoms, prolonged preoperative time and age less than 5 years are predictors of complicated appendicitis in pediatric patients. Materials and Methods: A retrospective case-control study was performed in 189 patients < 18 years post-operated for acute appendicitis between 2015-2019 in two hospitals. A bivariate and multivariate analysis of predictor factors of interest between patients with complicated and uncomplicated acute appendicitis was performed. Results: Of 189 patients included, 126 (66.67%) were uncomplicated appendicitis and 63 (33.33%) were complicated appendicitis. Bivariate analysis showed that neutrophils >10100 [OR = 2.12 (95% CI: 1-4.50), p = 0.047), symptom duration >72 hours [OR = 3.12 (95% CI: 1.19-8.21), P = 0.017] presented a significant association, while multivariate analysis confirmed that symptom duration (OR = 3.064, 95% CI = 1.152 - 8.151, P = 0.025) was an independent predictor of complicated acute appendicitis. Conclusions: Duration of symptoms >72 hours and neutrophils >10100 are predictors of complicated acute appendicitis in pediatric patients.
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Keywords
Apendicitis, Pediatría, Neutrófilos