Efecto antifúngico del extracto etanólico de Rumex crispus L. contra Candida albicans y Candida glabrata
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Date
2024-02-08
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Universidad Nacional de Trujillo
Abstract
La candidiasis vulvovaginal provocada principalmente por Candida albicans y Candida glabrata, se observa con mayor frecuencia en mujeres de edad reproductiva y conlleva entre un 15 a 20% de consultas ginecológicas. Existen plantas de fácil acceso con principios activos, tal es el caso de Rumex crispus L., cuyas propiedades son amplias contra diferentes microorganismos. Objetivo: Evaluar el efecto antifúngico del extracto etanólico de las hojas de Rumex crispus L. contra Candida albicans y Candida glabrata. Material y métodos: estudio experimental, con material biológico al extracto de Rumex crispus L. y población objetivo a las cepas de Candida albicans ATCC 66027 y Candida glabrata ATCC 66032. Resultados: la CIM frente a Candida albicans fue a partir de 25 mg/ml, la CIM frente a Candida glabrata fue a partir de 50 mg/ml, la CFM frente a Candida albicans fue a partir de 12.5 mg/ml y la CFM frente a Candida glabrata fue a partir de 25 mg/ml. Conclusión: se observó mejor efecto antifúngico del extracto etanólico de las hojas de Rumex crispus L frente a Candida albicans que a Candida glabrata.
Vulvovaginal candidiasis, caused mainly by Candida albicans and Candida glabrata, is observed more frequently in women of reproductive age and involves 15 to 20% of gynecological consultations. There are easily accessible plants with active ingredients, such is the case of Rumex crispus L., whose properties are broad against different microorganisms. Objective: To evaluate the antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. against Candida albicans and Candida glabrata. Material and methods: experimental study, with biological material to the extract of Rumex crispus L. and target population to the strains of Candida albicans ATCC 66027 and Candida glabrata ATCC 66032. Results: the MIC against Candida albicans was from 25 mg/ml, the MIC against Candida glabrata was from 50 mg/ml, the CFM against Candida albicans was from 12.5 mg/ml and the CFM against Candida glabrata was from 25 mg/ml. Conclusion: a better antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. was observed against Candida albicans than against Candida glabrata.
Vulvovaginal candidiasis, caused mainly by Candida albicans and Candida glabrata, is observed more frequently in women of reproductive age and involves 15 to 20% of gynecological consultations. There are easily accessible plants with active ingredients, such is the case of Rumex crispus L., whose properties are broad against different microorganisms. Objective: To evaluate the antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. against Candida albicans and Candida glabrata. Material and methods: experimental study, with biological material to the extract of Rumex crispus L. and target population to the strains of Candida albicans ATCC 66027 and Candida glabrata ATCC 66032. Results: the MIC against Candida albicans was from 25 mg/ml, the MIC against Candida glabrata was from 50 mg/ml, the CFM against Candida albicans was from 12.5 mg/ml and the CFM against Candida glabrata was from 25 mg/ml. Conclusion: a better antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. was observed against Candida albicans than against Candida glabrata.
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Keywords
Rumex Crispus, Candida Albicans, Candida Glabrata