Efecto antifúngico del extracto etanólico de Rumex crispus L. contra Candida albicans y Candida glabrata
dc.contributor.advisor | Ayala Ravelo, María Soledad | |
dc.contributor.author | Díaz Cubas, Felicita Yuliset | |
dc.contributor.author | Urbina Calderón, María Fiorelle | |
dc.date.accessioned | 2024-02-15T13:37:58Z | |
dc.date.available | 2024-02-15T13:37:58Z | |
dc.date.issued | 2024-02-08 | |
dc.description.abstract | La candidiasis vulvovaginal provocada principalmente por Candida albicans y Candida glabrata, se observa con mayor frecuencia en mujeres de edad reproductiva y conlleva entre un 15 a 20% de consultas ginecológicas. Existen plantas de fácil acceso con principios activos, tal es el caso de Rumex crispus L., cuyas propiedades son amplias contra diferentes microorganismos. Objetivo: Evaluar el efecto antifúngico del extracto etanólico de las hojas de Rumex crispus L. contra Candida albicans y Candida glabrata. Material y métodos: estudio experimental, con material biológico al extracto de Rumex crispus L. y población objetivo a las cepas de Candida albicans ATCC 66027 y Candida glabrata ATCC 66032. Resultados: la CIM frente a Candida albicans fue a partir de 25 mg/ml, la CIM frente a Candida glabrata fue a partir de 50 mg/ml, la CFM frente a Candida albicans fue a partir de 12.5 mg/ml y la CFM frente a Candida glabrata fue a partir de 25 mg/ml. Conclusión: se observó mejor efecto antifúngico del extracto etanólico de las hojas de Rumex crispus L frente a Candida albicans que a Candida glabrata. | |
dc.description.abstract | Vulvovaginal candidiasis, caused mainly by Candida albicans and Candida glabrata, is observed more frequently in women of reproductive age and involves 15 to 20% of gynecological consultations. There are easily accessible plants with active ingredients, such is the case of Rumex crispus L., whose properties are broad against different microorganisms. Objective: To evaluate the antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. against Candida albicans and Candida glabrata. Material and methods: experimental study, with biological material to the extract of Rumex crispus L. and target population to the strains of Candida albicans ATCC 66027 and Candida glabrata ATCC 66032. Results: the MIC against Candida albicans was from 25 mg/ml, the MIC against Candida glabrata was from 50 mg/ml, the CFM against Candida albicans was from 12.5 mg/ml and the CFM against Candida glabrata was from 25 mg/ml. Conclusion: a better antifungal effect of the ethanolic extract of the leaves of Rumex crispus L. was observed against Candida albicans than against Candida glabrata. | |
dc.format | application/pdf | |
dc.identifier.uri | https://hdl.handle.net/20.500.14414/20769 | |
dc.language.iso | es | |
dc.publisher | Universidad Nacional de Trujillo | |
dc.publisher.country | PE | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Rumex Crispus | |
dc.subject | Candida Albicans | |
dc.subject | Candida Glabrata | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.00.00 | |
dc.title | Efecto antifúngico del extracto etanólico de Rumex crispus L. contra Candida albicans y Candida glabrata | |
dc.type | info:eu-repo/semantics/bachelorThesis | |
dc.type.version | info:eu-repo/semantics/updatedVersion | |
renati.advisor.dni | 17873811 | |
renati.advisor.orcid | https://orcid.org/0000-0002-2059-5326 | |
renati.author.dni | 71853307 | |
renati.author.dni | 72950582 | |
renati.discipline | 912016 | |
renati.level | http://purl.org/pe-repo/renati/level#tituloProfesional | |
renati.type | http://purl.org/pe-repo/renati/type#tesis | |
thesis.degree.discipline | Medicina | |
thesis.degree.grantor | Universidad Nacional de Trujillo.Facultad de Medicina | |
thesis.degree.name | Médico Cirujano |