Efectividad del recuento leucocitario e índice neutrófilo/linfocito en el pronóstico de pancreatitis aguda

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dc.contributor.advisorGutiérrez Portilla, Wilmar Edy
dc.contributor.advisorEspinoza Llerena, Roberto José Manuel
dc.contributor.authorEspinola Rivera, Cynthia Katherine
dc.contributor.authorCortijo Marquina, Claudia Lucia
dc.date.accessioned2023-04-05T02:52:04Z
dc.date.available2023-04-05T02:52:04Z
dc.date.issued2023-03-27
dc.descriptionTo identify the effectiveness of the leukocyte count and neutrophil- lymphocyte index (INL) in the prognosis of acute pancreatitis (AP). MATERIAL AND METHOD: Analytical study of diagnostic tests, 269 medical records of patients with AP were selected; leukocyte count > 19,000, INL > 7.13, presence of mortality, organ failure (FO) and complications were placed in 2x2 tables, sensitivity (S), specificity (E), positive predictive value (PPV) and negative predictive value ( NPV), positive likelihood ratio (LR+) and negative likelihood ratio (LR-), if results were not significant, ROC and AUC curves would be used. RESULTS: A leukocyte count > 19,000 and INL > 7.13 did not predict mortality (S:27.27%, E:89.58%, PPV:10%, NPV:96.67% vs S:72.73%, E:47.1%, PPV:5.52% , NPV:97.6%), complications (S:14.94%, E:90.71%, PPV:43.33%, NPV:69.17% vs S:57.47%, E:48.63%, PPV:34.72%, NPV:70.63%) or OF (S:21.05%, E:89.64%, PPV:13.33%, NPV:93.75% vs S:57.89%, E: 46.61%, PPV:7.59%, NPV:93.6%). ROC and AUC curve were used, not finding a significant cut-off point. CONCLUSION: Leukocyte count and INL are not effective in the prognosis of AP, although their usefulness is suggested to identify a lower risk of mortality, complications and OF.es_PE
dc.description.abstractIdentificar la efectividad del recuento leucocitario e índice neutrófilo linfocito (INL) en el pronóstico de pancreatitis aguda (PA). MATERIAL Y MÉTODO: Estudio analítico de pruebas diagnósticas, se seleccionaron 269 historias clínicas de pacientes con PA; recuento leucocitario > 19 000, INL > 7.13, presencia de mortalidad, falla orgánica (FO) y complicaciones se colocaron en tablas 2x2, se halló sensibilidad (S), especificidad (E), valor predictivo positivo (VPP) y valor predictivo negativo (VPN), razón de verosimilitud positiva (LR+) y razón de verosimilitud negativa (LR-), en caso resultados no fueran significativos se usaría curvas ROC y AUC. RESULTADOS: Un recuento leucocitario > 19 000 e INL > 7.13 no pronosticaron mortalidad (S:27.27%, E:89.58%, VPP:10%, VPN:96.67% vs S:72.73%, E:47.1%, VPP:5.52%, VPN:97.6%), complicaciones (S:14.94%, E:90.71%, VPP:43.33%, VPN:69.17% vs S:57.47%, E:48.63%, VPP:34.72%, VPN:70.63%) ni FO (S:21.05%, E:89.64%, VPP:13.33%, VPN:93.75% vs S:57.89%, E: 46.61%, VPP:7.59%, VPN:93.6%). Se utilizó curva ROC y AUC, no encontrándose un punto de corte significativo. CONCLUSIÓN: Recuento leucocitario e INL no son efectivos en el pronóstico de PA, aunque, se sugiere su utilidad para identificar menor riesgo de mortalidad, complicaciones y FO.es_PE
dc.description.uriTesises_PE
dc.identifier.urihttps://hdl.handle.net/20.500.14414/16481
dc.language.isospaes_PE
dc.publisherUniversidad Nacional de Trujilloes_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_PE
dc.sourceUniversidad Nacional de Trujilloes_PE
dc.sourceRepositorio institucional - UNITRUes_PE
dc.subjectPancreatitis agudaes_PE
dc.subjectRecuento leucocitarioes_PE
dc.subjectIndice neutrófilo-linfocitoes_PE
dc.subjectFalla orgánicaes_PE
dc.subjectMortalidades_PE
dc.subjectComplicacioneses_PE
dc.titleEfectividad del recuento leucocitario e índice neutrófilo/linfocito en el pronóstico de pancreatitis agudaes_PE
dc.typeinfo:eu-repo/semantics/bachelorThesises_PE
renati.advisor.dni18825453
renati.advisor.dni41433382
renati.advisor.orcidhttps://orcid.org/0000-0002-0711-2406
renati.advisor.orcidhttps://orcid.org/0000-0003-2137-8005
renati.author.dni80963205
renati.author.dni72559340
renati.discipline912016
renati.jurorGuerra Martínez, José Rolando
renati.jurorPeña Quispe, Camilo Florentino
renati.jurorVásquez Palomino, Frank
thesis.degree.disciplineMedicinaes_PE
thesis.degree.grantorUniversidad Nacional de Trujillo.Facultad de Medicinaes_PE
thesis.degree.levelTítulo Profesionales_PE
thesis.degree.nameMédico Cirujanoes_PE
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